eldorado.tu-dortmund.de/signposting/describedby/1ed622f1-8e98-4c7d-85a6-2109ddefafbc
The effects of aB-crystallin on mitochondrial death pathway during hydrogen peroxide induced apoptos
remain largely unknown. In the present study, we discovered that aB-crystallin protected mouse myoblast C2C12 cells against oxidative stress-induced apoptosis. During hydrogen peroxide-induced apoptosis, aB [...] an interaction between aBcrystallin and p53 during hydrogen peroxide induced apoptosis. Both the NH2-terminal and COOH-terminal regions of aB-crystallin could interact with p53, suggesting two domains …
