eldorado.tu-dortmund.de/items/4cb8abf0-748a-4a2d-8091-a98d1e740b9b/full
Hepatoprotective effects of citric acid and aspartame on carbon tetrachloride-induced hepatic damage
3 %, AST by 47.8-70.6 %, ALP by 41.7-67.2 %, respectively compared to controls. Aspartame at 0.625 or 1.25 mg/kg reduced plasma ALT by 39.8-52.0 %, AST by 43.2-52.4 % and ALP by 50.0-68.5 %, respectively [...] respectively. Meanwhile, silymarin at 25 mg/kg reduced ALT, AST and ALP levels by 52.7, 62.2 and 64.7 %, respectively. On histology, citric acid at 1000 mg/kg resulted in near normalization of liver tissue. Vacuolar …
