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PDGFRA-wt ...................................... 40 3.4.4 Etablierung eines Kristallisationssystems für PDGFRA-T674I .............................. 43 3.4.5 Konstruktdesign der KIT-Kristallisationskonstrukte [...] 8PQA2 c-KIT kinase domain in complex with avapritinib derivative 4 8PQB3 c-KIT kinase domain in complex with avapritinib derivative 8 8PQC4 c-KIT kinase domain in complex with avapritinib derivative 9 8PQD5 [...] Biochemischen HTRF® TK-KinEASE Assay-Systems 30 3.4 Allgemeines über Strukturbiologische Untersuchungen .................................................... 31 3.4.1 Konstruktdesign der PDGFRA-Kristallisatio …

63 7 0. 77 4 0. 82 2 0. 99 5 C he m A xo n M ar vi n (V 20 .1 .0 ) 0. 85 6 1. 16 6 0. 74 4 0. 56 6 0. 86 5 0. 86 6 O P E R A (V 2. 5) * 2. 27 4 3. 05 9 -0 .7 54 1. 73 7 2. 18 2 0. 12 4 40 4.4 Discussion [...] external test sets (ngerprint: 4 096 bit MorganFeatures, radius=3) is given in gure 4.2. 31 4 Monoprotic pKa Prediction Figure 4.1: Distribution of the individual p K a values. Figure 4.2: (A ) Pairwise comparison [...] pK a1=7.68 pK a1=6.81 SM04 pK a1=6.02 pK a1=4.83 pK a1=5.68 SM05 pK a1=4.59 pK a1=4.19 pK a1=4.11 SM06 pK a1=3.03 pK a2=11.74 pK a1=3.42 pK a2=13.85 pK a1=4.28 CXM predicted p K a 2 outside of the range …

110 4.4 Possible factors influencing gene expression profile of hepatocytes in culture ........ 111 4.5 Minor role of NPC impurities on the expression of target genes during cultivation . 113 4.6 JNK [...] (ECM) ...................................... 83 3.4 3.4.1 Characterization of the non-parenchymal cells (NPC) fraction .............................. 83 3.4.1 Influence of non parenchymal cells (NPC) ... [...] 107 4.1 Monolayer cultures induce proliferation independent of additional growth factors 108 4.2 Hepatocyte cultivation induces an in vivo-like inflammation response ..................... 108 4.3 Ove …

f221-wedde.dvi

500 600 47 9. 83 50 2. 52 2 52 0. 20 2 52 0. 94 4 32 6. 55 8 34 5. 43 4 34 7. 83 4 35 3. 97 4 43 3. 45 45 9. 64 4 45 4. 32 4 45 7. 25 2 48 0. 84 8 50 7. 47 4 51 7. 95 5 52 1. 06 2 Beehive DSR AODV DSDV (c) [...] the nodes Node Mobility BeeAdHoc DSR AODV DSDV 1-5 m/s 6.2 1.4 1.8 2.4 1-10 m/s 5.5 1.3 2.4 2.6 1-15 m/s 6.1 1.0 1.6 2.6 1-20 m/s 11.4 1.1 1.4 3.3 Table 3: Effect of varying speed on Network life the algorithms [...] 90 92 94 96 98 100 98 .2 9 98 .5 5 98 .7 98 .7 1 98 .3 5 98 .4 8 98 .5 2 98 .5 7 95 .9 3 96 .4 3 96 .3 96 .3 1 97 .8 3 98 .2 2 98 .4 1 98 .4 8 Beehive DSR AODV DSDV (a) Packet delivery ratio send rate(packet/s) …

InformationsExtraktion.dvi

Retrieval . . . . . . . . . . . . . . 4 3.2 Vor- & Nachteile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 4 Informationsextraktionsschritte 4 4.1 Named Entity recognition (NE) . . . [...] . . . . . . . 5 4.2 Coreference Resolution (CO) . . . . . . . . . . . . . . . . . . . . . . . . . 5 4.3 Template Element construction (TE) . . . . . . . . . . . . . . . . . . . . 5 4.4 Template Relation [...] n en ts pr ec he n- de n T ex t is t. P G -4 0 2 In fo rm a ti o n se x tr a k ti o n C h ri st ia n H ü p p e < 0 . 2 1 . 3 . 9 5 . 1 4 . 1 2 . 1 1 . e d 4 7 + @ a n d r e w . c m u . e d u . 0 > T y …