eldorado.tu-dortmund.de/items/a2c2a5ef-eda0-4a40-b81a-900687d350b1/full
Antimicrobial and antioxidative activities of 1-adamantylthio derivatives of 3-substituted pyridines
2-(1-adamantylthio)-3-ethoxypyridine (4a), 2-(1-adamantylthio)-3-acetoxypyridine (4b), N-acetyl-2-(1-adamantylthio)-3-acetamidopyridine (4c), 2-(1-adamantylthio)-3-bromopyridine (4d), 2-(1-adamantylthio)-5-hyd [...] Particularly, the thiopyridines 4c, 5 and 6 are the most active compounds, displaying complete inhibition against ß-hemolytic Streptococcus group A at 30 µg/mL. These pyridyl sulfides 4a-d, 5 and 6 represent a [...] was analyzed using the DPPH assay. The sulfides 4a-d, 5 and 6 show only a weak antioxidative activity. In contrast the 2-(1-adamantylthio)-3-bromopyridine (4d) shows the highest radical scavenging activity …
