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Microsoft Word - Saadat_07_07_proof.doc
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expected ratio
1 2 3 4 5 6 7 8 9
10 11 12 13 14 15 16 17 18 19 20 21 22 X Y
47.1 46.9 48.9 53.3 50.3 50.1 46.2 48.4 49.8 50.1 45.8 51.7 53.7 54.1 48.2 49.5 37.3 54.4 50.1 45.5 58.8 49.3 47.6 61 [...] mosomes 11, 12, 14, 16, 17, 19, 20 and 22.
Also significantly lower gene density for chromosomes 2, 3, 4, 13, 18, 21 and Y. Previously Musio et al., (2002) reported the same correlation based on the about [...] distribution of genes on human chromosomes as studies by in situ nick translation. Genome 1992;35:890-4.
Hecht F. Fragile sites, cancer chromosome breakpoints, and oncogenes all cluster in light G bands. …