eldorado.tu-dortmund.de/collections/f2a2e21d-7fd2-443a-8f9f-c0f4d0d8a0fe
Lehrstuhl für Biologisch-Chemische Mikrostrukturtechnik
group 1: Abcb1, Ugt1a6, Gsta5, Gsta2, Hsf1, Nqo1, Apex1, Bax, Cdkn1a, Gadd45a, Mt1a, Sds, Mdm2, Myc) and one gene group which is active during cell proliferation (gene group 2: Mcm6, Cdc2, Hdc, 3-Pgdh, [...] biologische Aktivität als Protease-Inhibitoren untersucht werden. Für die Naturstoffklasse der 3-Amino-6-Hydroxy-2-piperidon(Ahp)-Cyclodepsipeptide, die als nicht-kovalente Serin-Protease-Inhibitoren bekannt [...] fibroblast-like Ad-MSCs. Generated differentiated cells had higher phase I (CYP1A1/2, CYP2E1, CYP2B6, CYP3A4) and phase II activities compared to the undifferentiated cells. A strong expression of CYP3A7 …