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and 7.2 mg/kg, respectively. In the liver, MDA decreased by 18.7, 30.7 and 49.4 % and GSH increased by 150.3, 204.8 and 335.4 % following trimetazidine administration at 1.8, 3.6 and 7.2 mg/kg. Meanwhile [...] ha
rid e
+ TMZ 1. 8 m
g/k g
+ TMZ 3. 6 m
g/k g
+ TMZ 7. 2 m
g/k g
0.0 0.5 1.0 1.5 2.0 2.5 3.0 3.5 4.0 4.5
* +
*
+
B ra
in G
SH ( µ
m ol
/g ti
ss ue
)
Figure 1B
EXCLI Journal 2011;10:162-172 – ISSN 1611-2156 [...] with timetazidine resulted in significant in- crease in GSH by 150.3 %, 204.8 and 335.4, respectively (3.68 ± 0.26, 4.48 ±
0.22 and 6.40 ± 0.28 for trimetazidine doses of 1.8, 3.6 and 7.2 mg/kg, respectively …
