eldorado.tu-dortmund.de/items/0fd4d781-be55-4655-bbc8-0a09ce395aec/full
Protective effect of L-ornithine-L-aspartate and silymarin on chemically induced kidney toxicity and
was induced by the administration of carbon tetrachloride (CCl4) for 2 weeks (2.0 gm/kg twice a week). In two separate groups, along with CCl4 animals were also treated with either lornit (200 mg/kg) or [...] hepatic and renal LPO, alterations in the concentrations of serum triiodothyronine (T3), thyroxine (T4), glucose and insulin and in hepatic type-1 iodothyronine 5’monodeiodinase (5’DI) activity were considered [...] also studied. Lornit or silymarin administration reversed almost all the toxic effects exhibited by CCl4 including enhanced tissue LPO, serum ALT, AST and ALP activities and the concentrations of insulin and …
