eldorado.tu-dortmund.de/items/a5ac2772-341f-4224-ad69-62c7631fd357
Role of WNT1-inducible signaling pathway protein-1 (WISP1) in liver injury
We have discovered that WISP1 (Wnt1-inducible signaling pathway protein-1) also named CCN4, is induced upon CCl4-induced liver damage and may play an important role in the remodeling process of the ext [...] Additionally, gene expression analysis and Sirius Red staining showed differences in the development of CCl4-induced fibrosis between WISP1 wild type and knockout mice. Upregulation of collagen type I and α-SMA [...] fibrosis.
Description
Table of contents
Keywords
WISP1 , Liver , Migration , HSC , ECM , Collagen , CCl4
Subjects based on RSWK
Leber , Lebererkrankung
Citation
URI
http://hdl.handle.net/2003/40035 http://dx …